Liverpool finished 2016 second in the Premier League with a 1-0 victory over third-placed Manchester City on Saturday.
A summary of Sunday's action in the Premier League.
Arsenal snapped a season-long jinx against Newcastle United with a nervy 1-0 win in their last Premier League home game on Sunday.
Both Manchester clubs remain unbeaten in the league with City atop the standings on 22 points and United two points behind after eight league games, followed by Tottenham Hotspur and Watford in third and fourth respectively.
Arsenal exacted sweet revenge on West Ham United with a 6-0 away thrashing to stay right in the thick of the Premier League title race.
Chelsea and Manchester City tightened their stranglehold on the Premier League title race on Saturday, recording victories over struggling clubs to stretch further clear of their increasingly forlorn pursuers.
Mohamed Salah's early penalty in the return match on Thursday gave Liverpool a 1-0 victory in Italy but Klopp's side went out 3-1 on aggregate.
Champions Manchester City slipped to a shock first Premier League defeat of the season at Wolverhampton Wanderers on Saturday, while Manchester United's campaign of woe continued with a loss to Crystal Palace.
IMAGES from EPL match played between Manchester City and Chelsea on Sunday
LeicesterCity went level on points with Premier League leaders Arsenal after drawing 0-0 with title rivals ManchesterCity at the King Power Stadium on Tuesday.
It was a third successive 0-0 draw for United after a stalemate at Chelsea on Sunday and against Real Sociedad last Thursday which completed a 4-0 aggregate win over the Spanish side in the Europa League.
The top four failed to muster a goal on Saturday as Chelsea, Liverpool and Manchester United drew 0-0 while Arsenal went down 3-0 at Manchester City. Premier League leaders Chelsea could find no way through Newcastle United at Stamford Bridge. Liverpool had the same problem at home to Fulham and third-placed Manchester United were held 0-0 in a lively game at Aston Villa.
Newcastle United produced an astonishing fightback to draw 4-4 at home to Arsenal on Saturday after trailing 4-0 with just 26 minutes gone in the Premier League on Saturday.
Manchester United manager Alex Ferguson predicted on Friday the Premier League title will be won by either his team or their fierce rivals Manchester City.
Pep Guardiola is pleased with the Premier League side's improvement and form over the past two months but will not make any premature comparison with his former clubs.
'I'm probably one of the only ones that disagrees, for the simple fact that we only had three games that we were below standard.'
Manchester City host Tottenham Hotspur on Saturday on the back of a record 15 successive English Premier League wins, and on the basis of their visitors' recent away form, a 16th victory appears to be the likely outcome.
Runaway Premier League leaders Manchester City beat champions Chelsea 1-0 at the Etihad Stadium on Sunday to extend their lead to 18 points and leave the London side further adrift from the Champions League qualification spots.
Images from the English Premier League matches played on Sunday night.
Images from Sunday's action in the Premier League.
Images from the English Premier League matches played on Wednesday night.
The following is a look back on key moments in the thrilling Premier League title race, won by Manchester City on Sunday:
The teams clash at the Etihad stadium on Sunday (1700 IST) with United three points clear of champions City.
Didier Drogba scored both goals for the leaders in a 2-0 win over Middlesbrough and champions Arsenal could only scrape a 1-1 draw with Manchester City.
Arsenal were held to a 1-1 Premier League draw by London rivals Fulham on a grey wet Sunday at Craven Cottage as Raul Jimenez scored early for the hosts and William Saliba equalised for the visitors at the start of the second half.
Blackpool and Birmingham City were relegated and Manchester City took third place on a dramatic final day of the Premier League season on Sunday.
Skipper Robin van Persie scored a hat-trick as Arsenal beat Chelsea 5-3 in a remarkable Premier League match at Stamford Bridge but Manchester City stayed top of the Premier League with a 3-1 home win over Wolverhampton Wanderers on Saturday.
Manchester City squandered a gilt-edged opportunity to close the gap on Premier League leaders Chelsea when they let slip a two-goal lead to draw 2-2 at home to struggling Burnley on Sunday.
IMAGES from the English Premier League matches played on Sunday.
Wayne Rooney produced a spectacular overhead kick to earn Manchester United a 2-1 victory over Manchester City and a seven-point lead in the Premier League on Saturday.
Premier league Leaders Manchester City piled the pressure on Manchester United with a 2-0 victory over Bolton Wanderers on Saturday to move five points clear of their neighbours.
Manchester United secured the point they needed to finish second in the Premier League with a dull 0-0 draw at West Ham United on Thursday.
IMAGES from the EPL matches played on Wednesday
Bundesliga leaders Bayern Munich powered past third-placed Eintracht Frankfurt 4-0 with an impressive display of high-pressing football on Sunday.
The in-form north London club travel to the Etihad Stadium five points behind Roberto Mancini's City in third place and two behind second-placed Manchester United, who face Arsenal at the Emirates on what could be a pivotal day at the top.
Manchester City came from behind to beat Bolton Wanderers 4-2 to keep their 100 percent home record and go fourth in the English Premier League.
Gareth Bale's superb double fired Tottenham Hotspur to a convincing 2-0 win at Norwich City Tuesday and narrowed the gap on Premier League leaders Manchester City and Manchester United to seven points. The pacey Welsh international took his league tally this season to seven goals, lifting third-placed Spurs, who have a game in hand on the two Manchester clubs, up to 38 points from 17 matches.
The "noisy neighbours" have been generally a bit quieter in recent weeks and should Manchester United beat Manchester City at Old Trafford on Saturday their title claims will be just about silenced.
Antonio Conte said his Chelsea players were fatigued after only 30 minutes of their 1-0 loss to Manchester City.
Alvaro Negredo and Sergio Aguero combined to help ManchesterCity bounce back from their Bayern Munich mauling by beating Everton 3-1 at the Etihad Stadium in the Premier League on Saturday.
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